If you wish to earn a Commercial Pilot License issued by the Directorate General of Civil Aviation (DGCA) in short a DGCA CPL License the eligibility criteria clearly state that you must have completed your 10+2 (or equivalent) with Physics Chemistry and Mathematics (PCM).
Without Mathematics in your 10+2 qualification you are not eligible under the standard criteria for admission to a DGCA approved flying training organization for CPL training. In fact the exact wording is 10+2 with Physics Chemistry and Mathematics or equivalent engineering/polytechnic diploma .
Yes there is a pathway though it requires extra effort and time. The same eligibility page notes that Non PCM background students can give PCM exam through NIOS" (the National Institute of Open Schooling) to meet the Mathematics and Physics requirement.
So if you have for example completed 10+2 with Biology or Commerce but not Maths you would need to take and pass the relevant Mathematics (and Physics) exam through NIOS or another recognised equivalent. Once you fulfill that requirement, you become eligible for the CPL training programme and the subsequent issuance of the DGCA CPL licence.
As a commercial pilot you must understand a lot of technical mathematical and scientific concepts: aerodynamics navigation flight performance meteorology aircraft systems instrument flying etc. Having Maths (along with Physics and Chemistry) in your educational background shows that you are equipped to handle these academic demands. That's why DGCA includes Maths in the eligibility criteria.